Where
Breakthroughs
Fluorish

Investing in early-stage start-ups at the intersection of Artificial Intelligence and Medical Technology

Meet our Team

Our Approach

A specialist venture capital fund built by founder-operators. Embedded in the UC San Diego innovation ecosystem. Committed to helping founders and their breakthrough innovations flourish.

Exceptional Access

We discover exceptional companies early through one of the nation's leading healthcare ecosystems

Founder Partnership

We work alongside founders to provide resources, navigate key decisions, and accelerate execution

Long-Term Value

We help companies build the relationships, networks, and momentum to maximize success

ReefHaven Portfolio

AI-Enabled Surgical Navigation

Precision Oncology Powered by AI

Next Generation Stroke Intervention

Representative Prior Investments

Logo for Boston Scientific
Logo for Boston Scientific
Logo for Edwards Lifesciences
Logo for Edwards Lifesciences

Founder-Operators Turned Investors

We’ve founded and built healthcare companies from concept to successful exits to the likes of Johnson & Johnson, AbbVie, and Medtronic. Having sat on both sides of the table, we bring a founder-operator perspective to our partners.

Garrett Smith, PhD

Managing Partner

Nicholas Mourlas, PhD

Investment Partner

Advisory Board

Our advisory board combines extensive venture capital experience, clinical expertise, and academic-industry translation know-how.

Our Ecosystem Advantage

Embedded Within An Innovation Ecosystem

Our partnership with the University of California San Diego provides unique access to emerging innovations while creating opportunities to share entrepreneurial insights with students, faculty, and clinicians.

ReefHaven works closely with the MedTech Accelerator in the Jacobs School of Engineering, the Schools of Medicine, Business, Biological Sciences, and Office of Innovation and Commercialization.

Image of an abstract circular object

What We Invest In

  • Dark image with faint glowing blue lines forming a circular, spiral, or net-like pattern.

    AI-enabled healthcare platforms

  • Digital grid pattern of blue lines creating a 3D spherical shape on a black background.

    Next-generation medical devices

  • Abstract image featuring swirling lines in shades of purple, pink, and blue on a dark background.

    Precision diagnostics

  • Close-up of a surface with many small blue bubbles or beads, creating a textured pattern with shiny reflections and a smooth, flowing appearance.

    Intelligent robotic systems

News

Connect with Us.

We believe that the most transformative healthcare companies emerge from strong innovation ecosystems. We work closely with founders, investors, strategics, and stakeholders across healthcare. If you would like to explore areas of shared interest, we welcome a conversation.